• Species Reactivity

  Mouse

• Specificity

  Detects mouse CCR3. Specifically stains mouse CCR3 transfectants but not the parental cell lines. Does not cross?react with Y3 cells transfected with human CCR3.

• Source

  Monoclonal Rat IgG2a Clone # 83103

• Immunogen

  Y3 rat myeloid cell line transfected with mouse CCR3    
  Met1-Phe359    
  Accession # P51678

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 μg/10    ⁶ cells

  Mouse CCR3 transfected Y3 cells

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CCR3

CCR3 is a G protein-linked seven transmembrane receptor that is activated by several different chemokines. It is expressed on subsets of granulocytes, monocytes, T cells and epithelial cells.

• Entrez Gene IDs:

  1232 (Human); 12771 (Mouse); 117027 (Rat); 448802 (Canine)

• Alternate Names:

  b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; CCR3; CCR-3; CD193 antigen; CD193; chemokine (C-C motif) receptor 3; CKR3CC-CKR-3CMKBR3CD193; eosinophil CC chemokine receptor 3; Eosinophil eotaxin receptor; MGC102841