詳細(xì)說(shuō)明
別名: 2-[[2-(2-Bromo-4-methylphenoxy)ethyl]thio]-pyrimidine
經(jīng)驗(yàn)分子式(希爾表示法) C13H13BrN2OS
分子量 325.22
產(chǎn)品名稱
Biochem/physiol Actions
ZLN024 is an allosteric activator of AMPK hetero-trimers. The compound ZLN024 protects against dephosphorylation of Thr172, which is critical for activity, and antagonizes AMPK autoinhibition. ZLM024 improves glucose tolerance and lowers total cholesterol levels in db/db mice.
性質(zhì)
assay | ≥98% (HPLC) |
form | powder |
color | white to beige |
solubility | DMSO: soluble20 mg/mL, clear |
storage temp. | 2-8°C |